Category Archives: Neurology

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes


Vanda A. Lennon, M.D., Ph.D., with the Departments of Laboratory Medicine and Pathology and Neurology, discusses research that identifies critical properties of neuromyelitis optica, a potentially debilitating neurological disease that is often misdiagnosed as multiple sclerosis (MS). Dr. Lennon’s team … Continue reading

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The incidence of MCI differs by subtype and is higher in men: The Mayo Clinic Study of Aging


Rosebud O. Roberts, M.B.Ch.B. with the Division of Epidemiology, discusses a study that measured the incidence of MCI and its subtypes using published criteria. Results showed a statistically significant difference between incidence rates among men and women. The study also … Continue reading

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Inflammatory cortical demyelination in early multiple sclerosis


Claudia F. Lucchinetti, M.D. of the Department of Neurology at Mayo Clinic in Rochester, Minn., discusses a study that provides definitive evidence that inflammatory disease of the gray matter commences early in the pathogenesis of some cases of multiple sclerosis. An … Continue reading

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New England Journal of Medicine article explores mild cognitive impairment


In the June 2011 issue of the New England Journal of Medicine, Ronald C. Petersen, M.D., Ph.D. with the Department of Neurology presents a case vignette highlighting mild cognitive impairment (MCI). Dr. Petersen presents evidence supporting various strategies, reviews formal … Continue reading

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Flow diversion for intracranial aneurysm


Guiseppe Lanzino, M.D., of the Department of Neurosurgery discusses the pipeline embolization device, a new therapeutic approach for patients with large cerebral aneurysms located along the proximal segment of the intracranial carotid artery. Large, giant and wide-necked aneurysms are traditionally challenging … Continue reading

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